ABSTRACT Intramuscular vaccination of mice with the naked pBI-11 DNA plasmid targeting E6 and E7 of HPV16 and HPV18 via a conventional syringe and needle generates human papillomavirus (HPV) antigen-specific CD8+ T cell-mediated immune responses and therapeutic effects against the TC-1 tumor model.However, delivery of DNA vaccines by this method is

A stochastic continuous-time Markov chain tuberculosis model with fast-slow progression and relapse is established to HEALTHY HEART CARDIOTALITY explore the impact of the demographic variation on TB transmission.At first, the extinction threshold and probability of the disease extinction and outbreak are obtained by applying the multitype Galton-Wa

To understand the error sources present in inertial sensors, both the white (time-invariant) and correlated noise sources must be properly characterized.To understand both sources, the standard approach (IEEE standards 647-2006, 952-2020) is to compute the Allan variance of the noise and then use human-based interpretation of linear trends to estim

Although appendiceal endometriosis is rare, appendix is the second most common site of intestinal endometriosis.Clinical diagnosis is difficult and histopathology is the only way to establish the diagnosis.We present a case of chronic pelvic pain secondary to appendiceal endometriosis and a review of the literature.There are no pathognomonic criter

Breeding apples is a long-term endeavour and it is imperative that new cultivars are selected to have outstanding consumer appeal.This study has taken the approach of merging sensory science with genome wide association analyses in order to map the human perception of apple flavour and texture onto the apple genome.The goal was to identify genomic